/*-----------------------------------*\
  PAGE
\*-----------------------------------*/

.jvadsection {
	margin-bottom: 64px;
}

.basic.bshort {
	max-width: 1400px;
}

.jvs-intro {
	text-align: center;
	margin-bottom: 24px;
}

.jvs-intro h2 {
	margin-bottom: 0;
	line-height: 1.4;
}

#footnotes .basic p:nth-of-type(3) {
	margin-top: 24px;
}

@media only screen and (min-width: 768px) {

	.jena-vad .row {
		align-items: center;
	}

	.jvs-intro {
		margin-bottom: 32px;
	}

}

@media only screen and (min-width: 1024px) {

	.jvadsection {
		margin-bottom: 96px;
	}

	.jvs-intro {
		margin-bottom: 36px;
	}

}

@media only screen and (min-width: 1280px) {

	.jvadsection {
		margin-bottom: 120px;
	}

	.jvs-intro {
		margin-bottom: 48px;
	}

}

@media only screen and (min-width: 1440px) {

	.jvadsection {
		margin-bottom: 140px;
	}

}

/*-----------------------------------*\
  HERO
\*-----------------------------------*/

#jvadhero {
	padding: 196px 0 60px;
	background: url(../img/artisthero-sm.jpg) no-repeat left top;
	background-size: cover;
	margin-bottom: 48px;
}

#jvadhero.atsection {
	margin-bottom: 0;
}

.jvadlogo {
	width: 160px;
	margin-bottom: 15px;
	opacity: 0; transform: translateY(30px);
	transition: all 0.7s ease-in-out 0.4s;
}

#jvadhero h1 {
	font-weight: 400;
	margin-bottom: 12px;
}

.hero.inview .jvadlogo {
	opacity: 1; transform: translateY(0);
}

#jvadhero.hero p {
	margin: 0;
}

#jvadhero .btn {
	z-index: 2;
	margin-top: 16px;
}

@media only screen and (min-width: 768px) {

	#jvadhero {
		padding: 0;
		background: url(../img/artisthero.jpg) no-repeat left top;
		background-size: cover;
		aspect-ratio: 1.8 / 1;
		margin-bottom: 64px;
	}

	#jvadhero .basic {
		display: flex; height: 100%;
		align-items: center;
		max-width: 1560px;
	}

	.jvadlogo {
		width: 11.25vw;
		margin-bottom: 0.78125vw;
	}

	#jvadhero h1 {
		font-size: clamp(3rem, 3.125vw, 6rem);
		line-height: 1.3; margin-bottom: 15px;
	}

	#jvadhero.hero p {
		font-size: clamp(1.6rem, 1.04167vw, 2rem);
	}

	#jvadhero .btn {
		margin-top: 20px;
	}

}

@media only screen and (min-width: 1024px) {

	#jvadhero {
		aspect-ratio: 2 / 1;
		padding-top: 40px;
	}

}

@media only screen and (min-width: 1280px) {

	#jvadhero {
		aspect-ratio: 2.2 / 1;
		margin-bottom: 100px;
	}

	#jvadhero .basic {
		padding: 0 60px;
	}

}

@media only screen and (min-width: 1600px) {

	#jvadhero {
		aspect-ratio: 2.59 / 1;
	}

}

@media only screen and (min-width: 1920px) {

	#jvadhero {
		width: 100%;
		height: 740px;
	}

	.jvadlogo {
		width: 216px;
		margin-bottom: 15px;
	}

}

/*-----------------------------------*\
  OBJECTIVE
\*-----------------------------------*/

.ob-copy {
	margin-bottom: 30px;
	font-size: 2rem;
}

.ob-art {
	padding: 30px 4px;
	border-radius: 12px;
	background: #F5F5F5;
	text-align: center;
}

.obimg {
	width: 197px;
	margin: 0 auto 20px;
}

.jvad-caption {
	line-height: 1.3; opacity: 0.7;
	font-size: 1.2rem;
}

@media only screen and (min-width: 768px) {

	.ob-copy {
		margin-bottom: 0;
		font-size: 1.8rem;
		width: 44.3%;
	}

	.ob-art {
		width: 48%;
	}

}

@media only screen and (min-width: 1024px) {

	.ob-copy {
		font-size: 2rem;
	}

	.ob-art {
		padding: 58px 0 25px;
		border-radius: 16px;
	}

	.obimg {
		width: 54.5%;
		margin: 0 auto 40px;
	}

	.jvad-caption {
		font-size: 1.4rem;
	}

}

@media only screen and (min-width: 1280px) {

	.ob-copy {
		font-size: 2.4rem;
	}

}

/*-----------------------------------*\
  POPULATION
\*-----------------------------------*/

.popcontent {
	padding: 24px 16px;
	background: #f5f5f5;
	border-radius: 16px;
	color: #333D4D;
}

.pc-art {
	width: 140px;
	margin: 0 auto 16px;
}

.pcc-intro {
	color: #033065; font-size: 2rem;
	font-weight: 500; line-height: 1.3;
	margin-bottom: 16px;
}

@media only screen and (min-width: 768px) {

	.popcontent {
		padding: 36px 20px;
		border-radius: 24px;
	}

	.pc-art {
		width: 25%;
		margin: 0;
	}

	.pc-copy {
		width: 68.75%;
	}

}

@media only screen and (min-width: 1280px) {

	.popcontent {
		padding: 36px 40px;
		border-radius: 32px;
	}

	.pcc-intro {
		font-size: 2.4rem;
		margin-bottom: 20px;
	}

}

@media only screen and (min-width: 1440px) {

	.popcontent {
		padding: 64px 80px;
	}

	.pcc-intro {
		font-size: 2.7rem;
	}

	.pc-copy {
		font-size: 1.7rem;
	}

}

/*-----------------------------------*\
  REGISTRY
\*-----------------------------------*/

.regitem {
	border: 1px solid #D9D9DE;
	padding: 18px; border-radius: 12px;
	color: #333D4D; font-size: 1.3rem;
	margin-bottom: 20px;
}

.ri-label {
	display: flex; align-items: center;
	margin-bottom: 8px;
}

.ri-number {
	display: flex; align-items: center;
	justify-content: center; color: #fff;
	background: #C93F8C; color: #fff;
	width: 22px; height: 22px;
	font-size: 1rem; font-weight: 700;
	margin-right: 8px; border-radius: 50%;
}

.ri-label span {
	color: #1578C5; font-size: 1.1rem;
	letter-spacing: 0.08em; font-weight: 700;
}

.ri-title {
	font-size: 1.7rem; font-weight: 500;
	color: #033065; line-height: 1.3;
	margin-bottom: 8px;
}

.reg-art {
	background: #f5f5f5; border-radius: 12px;
	padding: 30px 16px; text-align: center;
}

.regimg {
	width: 205px; margin: 0 auto 20px;
	box-shadow: 0 4px 34px 0 rgba(0, 0, 0, 0.1);
}

@media only screen and (min-width: 768px) {

	.reg-list {
		width: 43.9%;
	}

	.reg-art {
		width: 48%;
		padding: 48px 16px;
	}

	.regimg {
		width: 67.1875%;
	}

	.regitem:last-of-type {
		margin-bottom: 0;
	}

}

@media only screen and (min-width: 1280px) {

	.reg-list {
		width: 43.9%;
	}

	.reg-art {
		width: 48%;
		padding: 48px 16px;
	}

	.regimg {
		width: 67.1875%;
	}

	.regitem {
		padding: 24px; border-radius: 24px;
		font-size: 1.5rem; margin-bottom: 24px;
	}

	.reg-art {
		padding: 88px 16px;
	}

	.ri-title {
		font-size: 2.2rem;
		margin-bottom: 8px;
	}

}


/*-----------------------------------*\
  STUDY
\*-----------------------------------*/

.jvadstudy-intro {
	margin-top: 12px;
}

.studyitem {
	color: #033065; display: flex;
	align-items: center; justify-content: center;
	background: #f5f5f5; border-radius: 16px;
	margin-bottom: 20px; height: 112px;
	text-align: center; font-size: 1.3rem;
	font-weight: 500;
}

.study-bigtext {
	font-size: 3.2rem; color: #1578C5;
	line-height: 1.2; 
}

.studyinfo {
	background: #f5f5f5; border-radius: 16px;
	padding: 20px;
}

.studyinfo-item {
	margin-bottom: 16px; font-size: 1.4rem;
	color: #033065;
}

.sii-intro {
	color: #1578C5; font-size: 1.1rem;
	letter-spacing: 0.08em; font-weight: 700;
	margin-bottom: 2px; text-transform: uppercase;
}

.studyinfo-item:last-of-type {
	margin-bottom: 0;
}

@media only screen and (min-width: 768px) {

	.study-toprow {
		display: grid;
		grid-template-columns: repeat(2, 1fr);
	    grid-column-gap: 24px;
	    margin-bottom: 32px;
	}

	.studyitem {
		margin-bottom: 0;
	}

	.studyinfo {
		padding: 28px 0 0; display: flex;
		flex-wrap: wrap;
	}

	.studyinfo-item {
		width: 50%; padding: 0 36px 28px;
		margin-bottom: 0;
	}

}

@media only screen and (min-width: 1024px) {

	.study-toprow {
	    margin-bottom: 36px;
	}

	.studyitem {
		border-radius: 20px; height: 224px;
		font-size: 1.8rem;
	}

	.study-bigtext {
		font-size: 7rem;
		letter-spacing: -0.02em;
		margin-bottom: 2px;
	}

	.studyinfo {
		padding: 28px 0;
	}

	.studyinfo-item {
		width: 27%; padding: 0 36px;
		border-left: 1px solid #D9D9DE;
	}

	.studyinfo-item:first-of-type {
		border: 0;
	}

	.studyinfo-item:first-of-type,
	.studyinfo-item:last-of-type {
		width: 23%;
	}

}

@media only screen and (min-width: 1280px) {

	.study-toprow {
	    margin-bottom: 48px;
	}

}

@media only screen and (min-width: 1440px) {

	.studyinfo-item {
	    font-size: 1.8rem; width: 30%;
	}

	.studyinfo-item:first-of-type,
	.studyinfo-item:last-of-type {
		width: 20%;
	}

}

/*-----------------------------------*\
  ELIGIBILITY
\*-----------------------------------*/

.eg-row {
	background: #f5f5f5; border-radius: 16px;
	padding: 20px;
}

.eg-intro {
	padding-bottom: 16px;
	border-bottom: 1px solid #D9D9DE;
	margin-bottom: 16px; font-size: 1.2rem;
	color: #6B758C;
}

.eg-smallintro {
	color: #1578C5; font-size: 1.1rem;
	letter-spacing: 0.08em; font-weight: 700;
	margin-bottom: 12px; text-transform: uppercase;
}

.eg-bigintro {
	color: #033065; font-size: 2rem;
	line-height: 1.2; margin-bottom: 12px;
}

.eg-list {
	list-style: none;
	color: #033065;
}

.eg-list li {
	position: relative; padding-left: 30px;
	margin-bottom: 12px;
}

.eg-list li:last-child {
	margin-bottom: 0;
}

.roundcheck {
	position: absolute; width: 20px;
	top: 1px; left: 0;
}

@media only screen and (min-width: 768px) {

	.eg-bigintro {
		font-size: 2.4rem;
	}

}

@media only screen and (min-width: 1024px) {

	.eg-row {
		padding: 0; display: flex;
	}

	.eg-intro {
		padding-bottom: 0; border-bottom: 0;
		margin-bottom: 0; display: flex;
		width: 39%; align-items: center;
		padding: 0 20px;
	}

	.eg-bigintro {
		font-size: 3rem;
	}

	.eg-listwrap {
		width: 61%; padding: 30px 20px;
		border-left: 1px solid #D9D9DE;
	}

	.eg-list li {
		padding-left: 38px;
		margin-bottom: 22px;
	}

	.roundcheck {
		width: 24px;
		top: 0; left: 0;
	}

}

@media only screen and (min-width: 1280px) {

	.eg-intro {
		padding: 0 32px 0 56px;
	}

	.eg-smallintro {
		margin-bottom: 14px;
	}

	.eg-bigintro {
		font-size: 3.6rem;
		margin-bottom: 14px;
	}

	.eg-listwrap {
		padding: 44px 48px 44px 56px;
	}

}


/*-----------------------------------*\
  MEASURES
\*-----------------------------------*/

.measurewrap {
	background: #f5f5f5; border-radius: 16px;
	padding: 20px 18px;
}

.eff, .endpoints {
	margin-bottom: 12px;
}

.m-smallintro {
	color: #1578C5;
	font-size: 1.1rem;
	letter-spacing: 0.08em;
	font-weight: 700;
	margin-bottom: 14px;
	text-transform: uppercase;
}

.pill {
	border: 1px solid #D9D9DE;
	background: #fff; display: inline-flex;
	align-items: center; padding: 0 10px;
	height: 26px; border-radius: 9999em;
	font-size: 1.2rem; font-weight: 500;
	color: #033065; margin-bottom: 6px;
}

/* ---- Timeline Track component ---- */
  .timeline-track {
    --tl-accent: #c93f8c;          /* dot + connector colour          */
    --tl-halo: rgba(201, 63, 140, 0.18); /* soft halo behind the dot  */
    --tl-connector: rgba(201, 63, 140, 0.30);
    --tl-label: #033065;           /* navy label colour               */
    --tl-dot: 14px;                /* solid centre dot size           */
    --tl-halo-size: 28px;          /* outer halo size                 */

    position: relative;
    display: flex;
    justify-content: space-between;
    margin: 0 auto;
  }

  /* connector line runs between the centres of the first and last dots */
  .timeline-track__connector {
    position: absolute;
    top: calc(var(--tl-halo-size) / 2 - 1px);
    left: calc(var(--tl-halo-size) / 2);
    right: calc(var(--tl-halo-size) / 2);
    height: 2px;
    background: var(--tl-connector);
  }

  .timeline-track__item {
    position: relative;
    z-index: 1;
    display: flex;
    flex-direction: column;
    align-items: center;
    flex: 0 0 auto;
  }

  /* halo */
  .timeline-track__marker {
    width: var(--tl-halo-size);
    height: var(--tl-halo-size);
    border-radius: 50%;
    background: var(--tl-halo);
    display: flex;
    align-items: center;
    justify-content: center;
  }

  /* solid dot */
  .timeline-track__marker::after {
    content: "";
    width: var(--tl-dot);
    height: var(--tl-dot);
    border-radius: 50%;
    background: var(--tl-accent);
  }

  .timeline-track__label {
    margin-top: 4px;
    font-size: 1.2rem;
    font-weight: 600;
    line-height: 1.4;
    color: var(--tl-label);
    text-align: center;
    white-space: nowrap;
  }
@media only screen and (min-width: 1280px) {

	.measurewrap {
		padding: 32px 40px;
	}

	.measuretop {
		display: flex;
	}

	.eff {
		margin-bottom: 0; width: 30%;
	}

	.endpoints {
		width: 70%; padding-left: 32px;
		border-left: 1px solid #D9D9DE;
		margin-bottom: 20px;
	}

	.pill {
		padding: 0 14px;
		height: 36px; 
		font-size: 1.4rem; 
		margin-bottom: 8px;
		margin-right: 3px;
	}

	.pill:last-of-type {
		margin-right: 0;
	}

	.pill span {
		display: inline-block;
	}

	.pill span:before {
		content:""; display: inline-block; position: relative;
		width: 6px; height: 6px; border-radius: 50%;
		background: #C93F8C; margin-right: 8px;
		transform: translateY(-2px);
	}

	.visits {
		display: flex; align-items: center;
		padding-top: 28px;
		border-top: 1px solid #D9D9DE;
	}

	.timelinewrap {
		width: 85%;
	}

	.visitintro {
		width: 15%;
	}

	.visitintro .m-smallintro {
		margin-bottom: 0;
	}

	.timeline-track__label {
		font-size: 1.6rem;
	}

	.timeline-track__connector {
		left: 24px;
	}

}

/*-----------------------------------*\
  LOCATOR
\*-----------------------------------*/


/*-----------------------------------*\
  CONTACT
\*-----------------------------------*/

.jvcwrap {
	background: #f5f5f5;
	border-radius: 16px;
	padding: 24px 16px;
}

.jvcw-intro {
	padding-bottom: 20px;
	border-bottom: 1px solid rgba(0, 0, 0, 0.15);
	margin-bottom: 20px;
}

.jvcw-intro h2 {
	margin-bottom: 0;
}

.jvcw-option {
	margin-bottom: 18px;
}

.jvcw-option:last-of-type {
	margin-bottom: 0;
}

.option-label {
	color: #333D4D; font-size: 1.4rem;
	margin-bottom: 10px;
}

.option-email {
	display: flex; align-items: center;
	justify-content: center; border-radius: 9999em;
	border: 1px solid rgba(3, 48, 101, 0.30);
	background: #FFF; color: #033065; height: 52px;
	font-weight: 500; font-size: 1.6rem;
}

.icn-mail {
	width: 32px;
	margin-right: 12px;
}

@media only screen and (min-width: 1024px) {

	.jvcw-row {
		display: grid;
		grid-template-columns: repeat(3, 1fr);
	    grid-column-gap: 10px;
	}

	.jvcw-option {
		margin-bottom: 0;
	}

}

@media only screen and (min-width: 1280px) {

	.jvcw-intro {
		padding-bottom: 32px;
		margin-bottom: 32px;
	}

	.jvcwrap {
		border-radius: 24px;
		padding: 36px 40px;
	}

	.option-email {
		height: 64px;
		font-size: 1.8rem;
	}

}

@media only screen and (min-width: 1440px) {

	.jvcwrap {
		padding: 56px 64px;
	}

	.jvcw-row {
	    grid-column-gap: 32px;
	}

}

/*-----------------------------------*\
  LOCATOR
\*-----------------------------------*/

.locator-inner {
	background: #f6f6f6;
	padding: 60px 16px;
	max-width: 1860px;
	margin: 0 auto;
}

.locator-content {
	max-width: 1560px;
	margin: 0 auto;
}

.locator-top {
	text-align: center;
	margin-bottom: 20px;
}

.locator-top p:last-of-type {
	margin-bottom: 0;
}

.locator-top h2 {
	margin-bottom: 10px;
}

#siteSearch {
	width: 288px; margin: 0 auto 40px;
	display: flex; justify-content: space-between;
}

input#zip {
	color: rgba(0, 0, 0, 0.60);
	font-size: 1.6rem;
	font-weight: 400;
	width: 188px; height: 40px;
	padding: 0 1.6rem;
	margin: 0; line-height: 38px;
	border-radius: 9999px;
	border: 1px solid #CECECE;
	background: #fff;
}

button#zipSearch {
	background: #1578C5; color: #fff;
	font-size: 1.1rem; font-weight: 500;
	padding: 0; width: 92px; height: 40px;
	border-radius: 9999px; text-align: center;
	text-transform: uppercase;
}

.locResults {
	margin-bottom: 10px;
	border: 1px solid #dfdfdf;
	border-radius: 16px;
	background: #FAFAFA;
	overflow: hidden;
	color: #000;
}

.siteInfo {
	padding: 16px;
}

.sitelogowrap {
	height: 18px;
	margin-bottom: 6px;
	display: flex;
	align-items: center;
}

.siteLogo {
	width: auto; height: 18px;
}

#ART-012.siteLogo {
	height: 12px;
}

.siteName {
	font-size: 1.8rem;
	font-weight: 500;
	line-height: 1.4;
	margin-bottom: 5px;
}

.siteLocation {
	font-size: 1.2rem;
	line-height: 1.5;
	margin-bottom: 12px;
}

.pi-info {
	margin-bottom: 16px;
}

.pi-details {
	display: flex;
	align-items: center;
}

.pi-details.pi2 {
	margin-top: 8px;
}

.pi-details.hidepi2 {
	display: none;
}

.pi-img {
	width: 30px;
}

.pi-name {
	font-size: 1.6rem;
	font-weight: 500;
	margin-left: 16px;
}

.contact-label {
	font-size: 1.2rem;
	margin-bottom: 8px;
	font-weight: 500;
	opacity: 0.56;
}

.crc-info {
	margin-bottom: 16px;
}

.crc-details.crc2 {
	margin-top: 10px;
}

.crc-details.hidecrc2 {
	display: none;
}

.crc-name {
	font-size: 1.4rem; font-weight: 500;
	margin-bottom: 6px; line-height: 1.2;
}

.sc-link {
	display: inline-block;
	vertical-align: top;
	font-size: 1.4rem; font-weight: 500;
	color: #000; text-decoration: underline;
	padding-left: 28px; line-height: 2rem;
}

.sc-email {
	background: url(../img/site/email-icon.svg) no-repeat left center;
	background-size: 20px;
}

.sc-phone {
	background: url(../img/site/phone-icon.svg) no-repeat left center;
	background-size: 20px;
}

.sc-directions {
	background: url(../img/site/map-icon.svg) no-repeat left center;
	background-size: 20px;
}

.sc-website {
	background: url(../img/site/web-icon.svg) no-repeat left center;
	background-size: 20px;
}

.mdot {
	display: inline-block;
	vertical-align: top;
	margin: 0 4px;
}

.btn-site {
	display: inline-flex; align-items: center;
	justify-content: center;
	width: 160px; height: 34px;
	border-radius: 9999px;
	border: 1px solid #1578C5;
	color: #1578C5; font-size: 1.1rem;
	text-transform: uppercase;
	font-weight: 500;
	margin-top: 16px;
}

.btn-site span, .icn-ext {
	display: inline-block;
}

.icn-ext {
	width: 10px; margin-left: 4px;
}


@media only screen and (min-width: 768px) {

	#locator {
		padding: 0 30px;
	}

	.locator-inner {
		padding: 60px 16px;
		border-radius: 24px;
	}

	.locator-top {
		margin-bottom: 24px;
	}

	#siteSearch {
		width: 380px;
	}

	input#zip {
		width: 272px; height: 48px;
		line-height: 46px;
	}

	button#zipSearch {
		font-size: 1.3rem;
		width: 100px; height: 48px;
	}

	#locResultsWrapper {
		display: grid;
		grid-template-columns: repeat(3, 1fr);
		grid-column-gap: 10px;
		max-width: 1700px;
		margin: 0 auto;
	}

	.locResults {
		margin-bottom: 0;
	}

	.siteName {
		font-size: 1.6rem;
	}

	.pi-img {
		width: 36px;
	}

}

@media only screen and (min-width: 1024px) {

	#locator {
		padding: 0 40px;
	}

	.locator-inner {
		padding: 60px 20px;
	}

}

@media only screen and (min-width: 1280px) {

	.locator-inner {
		padding: 80px 40px;
	}

	.locator-top h2 {
		margin-bottom: 24px;
	}

	.locator-top {
		font-size: 1.8rem;
	}

	.siteName {
		font-size: 1.8rem;
	}

	#locResultsWrapper {
		grid-column-gap: 20px;
	}

}

@media only screen and (min-width: 1440px) {

	#locResultsWrapper {
		grid-column-gap: 30px;
	}

	.siteInfo {
		padding: 24px;
	}

	.sitelogowrap {
		margin-bottom: 8px;
		height: 24px;
	}

	.siteLogo {
		height: 24px;
	}

	#ART-012.siteLogo {
		height: 18px;
	}

	.siteName {
		font-size: 2rem;
	}

	.siteLocation {
		font-size: 1.6rem;
		margin-bottom: 18px;
	}

	.pi-info {
		margin-bottom: 24px;
	}

	.piLabel {
		font-size: 1.4rem;
	}

	.piName {
		font-size: 1.8rem;
	}

	.contact-label {
		font-size: 1.4rem;
		margin-bottom: 10px;
	}

	.crc-info {
		margin-bottom: 24px;
	}

	.crc-name {
		font-size: 1.6rem; 
		margin-bottom: 8px;
	}

	.sc-link {
		font-size: 1.6rem; 
		padding-left: 32px; line-height: 2.4rem;
	}

	.sc-email {
		background: url(../img/site/email-icon.svg) no-repeat left center;
		background-size: 24px;
	}

	.sc-phone {
		background: url(../img/site/phone-icon.svg) no-repeat left center;
		background-size: 24px;
	}

	.sc-directions {
		background: url(../img/site/map-icon.svg) no-repeat left center;
		background-size: 24px;
	}

	.sc-website {
		background: url(../img/site/web-icon.svg) no-repeat left center;
		background-size: 24px;
	}

	.mdot {
		display: inline-block;
		vertical-align: top;
		margin: 0 6px;
	}

	.btn-site {
		width: 200px; height: 46px;
		font-size: 1.3rem;
		margin-top: 24px;
	}

	.icn-ext {
		width: 14px; margin-left: 8px;
	}

}